Limited Competition: NIGMS Mature Synchrotron Resources (MSR) for Structural Biology (P30 - Clinical Trial Not Allowed)

HHS-NIH11 PAR-27-068
Posted: Aug 31, 2026 12:00:00 AM EDT
Closes: 10/02/2028

Description

This Notice of Funding Opportunity (NOFO) supports "mature" resources at synchrotron facilities that provide user access to X-ray beamlines for static and dynamic imaging of biological systems ranging from molecules to organs. "Mature" refers to the techniques made available at the resource beamlines, which must be well established and provide utility to the communities they serve without requiring significant novel technology development. Applications may only request support for existing synchrotron resources that are currently supported by NIGMS funding. The facility is expected to be maintained or upgraded to current best practices, make its capabilities and availability known to the biomedical research community through outreach activities, and provide user training and support.This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Synopsis

This Notice of Funding Opportunity (NOFO) supports "mature" resources at synchrotron facilities that provide user access to X-ray beamlines for static and dynamic imaging of biological systems ranging from molecules to organs. "Mature" refers to the techniques made available at the resource beamlines, which must be well established and provide utility to the communities they serve without requiring significant novel technology development. Applications may only request support for existing synchrotron resources that are currently supported by NIGMS funding. The facility is expected to be maintained or upgraded to current best practices, make its capabilities and availability known to the biomedical research community through outreach activities, and provide user training and support.This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Eligibility

Eligible Applicants:
Native American tribal governments (Federally recognized) State governments Others (see text field entitled "Additional Information on Eligibility" for clarification) Private institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments For profit organizations other than small businesses Independent school districts Special district governments Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities
Requirement for Current NIGMS Support: This NOFO is limited to applicants requesting support for existing synchrotron resources that are currently supported by NIGMS funding. Applications cannot support resources whose funding ended more than 36 months prior to the application due date.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Funding Activity Categories

Health

CFDA Numbers

  • 93.859 - Biomedical Research and Research Training

Contact Information

Agency: National Institutes of Health
Contact: National Institutes of Health
Phone: 301-402-2541
MSR P30
MSRP30Mailbox@nih.gov

Additional Information

Document Type: synopsis
Opportunity Category: Discretionary
Version: 1
Last Updated: Aug 31, 2026 11:54:22 AM EDT

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