Development of Candidate Medical Countermeasures (MCMs) and Technologies Against Radiological/Nuclear or Chemical Threats (U01 Clinical Trial Not Allowed)
Posted: Sep 01, 2026 12:00:00 AM EDT
Closes: 10/09/2028
Description
The purpose of this notice of funding opportunity (NOFO) is to support research that advances understanding of the natural history of radiation or chemical exposures; develops relevant injury models; identifies and validates diagnostic tools, biomarkers, or triage technologies; and supports the development of effective medical countermeasures (MCMs) to mitigate or treat acute and/or delayed injuries resulting from radiological/nuclear or chemical public health emergencies.
Synopsis
The purpose of this notice of funding opportunity (NOFO) is to support research that advances understanding of the natural history of radiation or chemical exposures; develops relevant injury models; identifies and validates diagnostic tools, biomarkers, or triage technologies; and supports the development of effective medical countermeasures (MCMs) to mitigate or treat acute and/or delayed injuries resulting from radiological/nuclear or chemical public health emergencies.
Eligibility
Eligible Applicants:
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.
Funding Activity Categories
CFDA Numbers
- 93.233 - National Center on Sleep Disorders Research
- 93.279 - Drug Use and Addiction Research Programs
- 93.837 - Cardiovascular Diseases Research
- 93.838 - Lung Diseases Research
- 93.839 - Blood Diseases and Resources Research
- 93.840 - Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
- 93.846 - Arthritis, Musculoskeletal and Skin Diseases Research
- 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders
- 93.855 - Allergy and Infectious Diseases Research
- 93.867 - Vision Research
Contact Information
Agency: National Institutes of Health
Contact: National Institutes of Health
Email: RADCHEM_U01@mail.nih.gov
Phone: 301-402-2541
National Institute of Allergy and Infectious Diseases (NIAID)
RADCHEM_U01@mail.nih.gov
RADCHEM_U01@mail.nih.gov
Additional Information
Document Type: synopsis
Opportunity Category: Discretionary
Version: 1
Last Updated: Sep 01, 2026 07:55:04 AM EDT
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